ENTRY       EC 3.1.16.1
NAME        Spleen exonuclease
            3'-Exonuclease
            Spleen phosphodiesterase
CLASS       Hydrolases
            Acting on ester bonds
            Exonucleases active with either ribo- or deoxyribonucleic acids
            and producing other than 5'-phosphomonoesters
REACTION    Exonucleolytic cleavage in the 5'- to 3'-direction to yield
            3'-phosphomononucleotides
SUBSTRATE   RNA
            DNA
            H2O
PRODUCT     3'-Phosphomononucleotide
COMMENT     Preference for single-stranded substrate.  Similar enzymes:
            Lactobacillus acidophilus nuclease; B. subtilis nuclease; Salmon
            testis nuclease.  Formerly EC 3.1.4.18. (cf. EC 3.1.31.1).
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.16.1
            WIT (What Is There) Metabolic Reconstruction: 3.1.16.1
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