ENTRY EC 3.1.13.2
NAME Exoribonuclease H
CLASS Hydrolases
Acting on ester bonds
Exoribonucleases producing 5'-phosphomonoesters
REACTION Exonucleolytic cleavage to 5'-phosphomonoester oligonucleotides in
both 5'- to 3'- and 3'- to 5'-directions.
SUBSTRATE RNA
H2O
PRODUCT 5'-Phosphomonoester oligonucleotides
COMMENT Attacks RNA in duplex with DNA strand. Found in certain oncorna
viruses and animal cells.
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.13.2
WIT (What Is There) Metabolic Reconstruction: 3.1.13.2
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