ENTRY       EC 3.1.11.5
NAME        Exodeoxyribonuclease V
            E.coli exonuclease V
CLASS       Hydrolases
            Acting on ester bonds
            Exodeoxyribonucleases producing 5'-phosphomonoesters
REACTION    Exonucleolytic cleavage (in presence of ATP) in either 5'- to 3'-
            or 3'- to 5'-direction to yield 5'-phosphooligonucleotides
SUBSTRATE   Deoxyribonucleotide
            Double-stranded DNA
            Single-stranded DNA
            H2O
            ATP
PRODUCT     5'-Phosphooligonucleotide
            ADP
            Orthophosphate
COFACTOR    ATP
COMMENT     Preference for double-stranded DNA. Possesses DNA-dependent ATPase
            activity. Acts endonucleolytically on single-stranded circular
            DNA. Similar enzyme: Haemophilus influenzae ATP-dependent DNase.
GENES       ECO: b2819(recD) b2820(recB) b2822(recC)
            HIN: HI0942(recC) HI1321(recB) HI1322(recD)
            BSU: yrrC
            SYN: recB) sll1121(ECOLI_2748
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.11.5
            WIT (What Is There) Metabolic Reconstruction: 3.1.11.5
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