ENTRY EC 3.1.11.3
NAME Exodeoxyribonuclease (lambda-induced)
Lambda exonuclease
CLASS Hydrolases
Acting on ester bonds
Exodeoxyribonucleases producing 5'-phosphomonoesters
REACTION Exonucleolytic cleavage in the 5'- to 3'-direction to yield
5'-phosphomononucleotides
SUBSTRATE DNA
H2O
PRODUCT 5'-Phosphomononucleotides
COMMENT Preference for double-stranded DNA. Does not attack
single-strand breaks. Similar ezyme: T4, T5 and T7 exonucleases;
Mammalian DNase IV. Formerly EC 3.1.4.28.
STRUCTURES PDB: 1EXN
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.11.3
WIT (What Is There) Metabolic Reconstruction: 3.1.11.3
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