ENTRY EC 3.1.11.1
NAME Exodeoxyribonuclease I
E.coli exonuclease I
CLASS Hydrolases
Acting on ester bonds
Exodeoxyribonucleases producing 5'-phosphomonoesters
REACTION Exonucleolytic cleavage in the 3'- to 5'-direction to yield
5'-phosphomononucleotides
SUBSTRATE Deoxyribonucleotide
Single-stranded DNA
Glucosylated DNA
H2O
PRODUCT 5'-Phosphomononucleotide
COMMENT Preference for single-stranded DNA. The E. coli enzyme hydrolyses
glucosylated DNA. Similar enyzmes: Mammalian DNase III;
Exonuclease IV; T2- and T4-induced exodeoxyribonucleases. Formerly
EC 3.1.4.25.
GENES ECO: b2011(sbcB)
HIN: HI1377(sbcB)
SYN: sbcB) sll0448(ECOLI_1959
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.11.1
WIT (What Is There) Metabolic Reconstruction: 3.1.11.1
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