ENTRY EC 3.1.1.8
NAME Cholinesterase
Pseudocholinesterase
Butrylcholine esterase
Non-specific cholinesterase
Choline esterase II (unspecific)
Benzoylcholinesterase
CLASS Hydrolases
Acting on ester bonds
Carboxylic ester hydrolases
SYSNAME Acylcholine acylhydrolase
REACTION an Acylcholine + H2O = Choline + a Carboxylate
SUBSTRATE Acylcholine
Choline ester
H2O
PRODUCT Choline
Carboxylate
COMMENT Acts on a variety of choline esters and a few other compounds.
DISEASE MIM: 177400 Butyrylcholinesterase; Apnea, postanesthetic (3)
MOTIF PS: PS00122 F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G
PS: PS00941 [ED]-D-C-L-[YT]-[LIV]-[DNS]-[LIV]-[LIVFYW]-x-[PQR]
GENES HSA: BCHE
DBLINKS University of Geneva ENZYME DATA BANK: 3.1.1.8
WIT (What Is There) Metabolic Reconstruction: 3.1.1.8
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