ENTRY       EC 3.1.1.59
NAME        Juvenile-hormone esterase
            JH-esterase
CLASS       Hydrolases
            Acting on ester bonds
            Carboxylic ester hydrolases
SYSNAME     Methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyl-trideca-
            $2,6-dienoate acylhydrolase
REACTION    Methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-
            $2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-Epoxy-3,7,11-
            $trimethyltrideca-2,6-dienoate + Methanol
SUBSTRATE   Methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-
            $2,6-dienoate
            H2O
PRODUCT     (2E,6E)-(10R,11S)-10,11-Epoxy-3,7,11-trimethyltrideca-2,6-
            $dienoate
            Methanol
COMMENT     Demethylates the insect juvenile hormones, JH1 and JH3, but
            does not hydrolyse the analogous ethyl or isopropyl esters.
MOTIF       PS: PS00122  F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G
            PS: PS00941  [ED]-D-C-L-[YT]-[LIV]-[DNS]-[LIV]-[LIVFYW]-x-[PQR]
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.1.59
            WIT (What Is There) Metabolic Reconstruction: 3.1.1.59
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