ENTRY       EC 3.1.1.55
NAME        Acetylsalicylate deacetylase
            Aspirin esterase
CLASS       Hydrolases
            Acting on ester bonds
            Carboxylic ester hydrolases
SYSNAME     Acetylsalicylate O-acetylhydrolase
REACTION    Acetylsalicylate + H2O = Salicylate + Acetate
SUBSTRATE   Acetylsalicylate
            H2O
PRODUCT     Salicylate
            Acetate
COMMENT     Not identical with EC 3.1.1.1, 3.1.1.2, 3.1.1.7 or 3.1.1.8.  The
            activity of the liver cytosol enzyme is highest with acetyl esters
            of aryl alcohols, and thioesters are also hydrolaysed; the
            microsomal enzyme also hydrolyses some other negatively charged
            esters, with highest activity on esters of salicylate with long-
            -chain alcohols.
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.1.55
            WIT (What Is There) Metabolic Reconstruction: 3.1.1.55
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