ENTRY       EC 3.1.1.13
NAME        Sterol esterase
            Cholesterol esterase
            Cholesteryl ester synthase
            Triterpenol esterase
CLASS       Hydrolases
            Acting on ester bonds
            Carboxylic ester hydrolases
SYSNAME     Steryl-ester acylhydrolase
REACTION    a Steryl ester + H2O = a Sterol + a Fatty acid
SUBSTRATE   Steryl ester
            H2O
PRODUCT     Sterol
            Fatty acid
COMMENT     A group of enzymes of broad specificity, acting on esters of
            sterols and long-chain fatty acids, which may also bring about the
            esterification of sterols. Activated by bile salts.
PATHWAY     PATH: MAP00120  Bile acid biosynthesis
MOTIF       PS: PS00120  [LIV]-x-[LIVFY]-[LIVST]-G-[HYWV]-S-x-G-[GSTAC]
            PS: PS00122  F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G
            PS: PS00941  [ED]-D-C-L-[YT]-[LIV]-[DNS]-[LIV]-[LIVFYW]-x-[PQR]
GENES       HSA: LIPA(Hs.85226)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.1.13
            WIT (What Is There) Metabolic Reconstruction: 3.1.1.13
///