ENTRY       EC 3.1.1.1
NAME        Carboxylesterase
            Ali-esterase
            B-esterase
            Monobutyrase
            Cocaine esterase
            Procaine esterase
            Methylbutyrase
CLASS       Hydrolases
            Acting on ester bonds
            Carboxylic ester hydrolases
SYSNAME     Carboxylic-ester hydrolase
REACTION    a Carboxylic ester + H2O = an Alcohol + a Carboxylate
SUBSTRATE   Carboxylic ester
            H2O
            Vitamin A ester
PRODUCT     Alcohol
            Carboxylate
            Vitamin A
COMMENT     Wide specificity. The enzymes from microsomes also catalyse the
            reactions of EC 3.1.1.2, 3.1.1.5, 3.1.1.6, 3.1.1.23, 3.1.1.28,
            3.1.2.2, 3.5.1.4 and 3.5.1.13. Also hydrolyses vitamin A esters.
MOTIF       PS: PS00014  [KRHQSA]-[DENQ]-E-L>
            PS: PS00122  F-[GR]-G-x(4)-[LIVM]-x-[LIV]-x-G-x-S-[STAG]-G
            PS: PS00941  [ED]-D-C-L-[YT]-[LIV]-[DNS]-[LIV]-[LIVFYW]-x-[PQR]
GENES       BSU: nap ybfK
            SCE: YJL068C(J1102)
            HSA: CES1(HMSE) CES2(Hs.76688) ESA4 ESB3 ESD(Hs.82193)
DBLINKS     University of Geneva ENZYME DATA BANK: 3.1.1.1
            WIT (What Is There) Metabolic Reconstruction: 3.1.1.1
///