ENTRY       EC 2.7.7.48
NAME        RNA-directed RNA polymerase
            RNA nucleotidyltransferase (RNA-directed)
CLASS       Transferases
            Transferring phosphorus-containing groups
            Nucleotidyltransferases
SYSNAME     Nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
REACTION    Nucleoside triphosphate + RNA(n) = Pyrophosphate + RNA(n+1)
SUBSTRATE   Nucleoside triphosphate
            RNA(n)
PRODUCT     Pyrophosphate
            RNA(n+1)
COMMENT     Catalyses RNA-template-directed extension of the 3'- end of an RNA
            strand by one nucleotide at a time. Can initiate a chain de novo.
            See also EC 2.7.7.6.
            (EC 2.7.7.6 DNA-directed RNA polymerase)
PATHWAY     PATH: MAP00230  Purine metabolism
STRUCTURES  PDB: 1HAV  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.7.48
            WIT (What Is There) Metabolic Reconstruction: 2.7.7.48
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