ENTRY EC 2.7.7.28
NAME Nucleoside-triphosphate--hexose-1-phosphate
$ nucleotidyltransferase
NDPhexose pyrophosphorylase
CLASS Transferases
Transferring phosphorus-containing groups
Nucleotidyltransferases
SYSNAME NTP:hexose-1-phosphate nucleotidyltransferase
REACTION Nucleoside triphosphate + Hexose 1-phosphate = Pyrophosphate +
NDPhexose
SUBSTRATE Nucleoside triphosphate
Hexose 1-phosphate
GTP
D-Glucose 1-phosphate
D-Mannose 1-phosphate
PRODUCT Pyrophosphate
NDPhexose
GDPglucose
GDPmannose
COMMENT In decreasing order of activity, guanosine, inosine and adenosine
diphosphate hexoses are substrates in the reverse reaction with
either glucose or mannose as the sugar.
DBLINKS University of Geneva ENZYME DATA BANK: 2.7.7.28
WIT (What Is There) Metabolic Reconstruction: 2.7.7.28
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