ENTRY       EC 2.7.7.19
NAME        Polynucleotide adenylyltransferase
            NTP polymerase
            RNA adenylating enzyme
CLASS       Transferases
            Transferring phosphorus-containing groups
            Nucleotidyltransferases
SYSNAME     ATP:polynucleotide adenylyltransferase
REACTION    ATP + RNA(n) = Pyrophosphate + RNA(n+1)
SUBSTRATE   ATP
            RNA(n)
PRODUCT     Pyrophosphate
            RNA(n+1)
COMMENT     Also acts slowly with CTP. Catalyses template-independent
            extension of the 3'- and of a DNA strand by one nucleotide at a
            time. Cannot initiate a chain de novo. The primer, depending on
            the source of the enzyme, may be an RNA or DNA fragment or
            oligo(A) bearing 3'-OH terminal group. See also EC 2.7.7.6.
GENES       ECO: b0143(pcnB)
            HIN: HI0063(pcnB)
            HPY: HP0640(papS)
            BSU: papS(ypjI)
            SYN: sll0825(pcnB) sll1253(pcnB)
            SCE: YKR002W(PAP1)
            HSA: OIAS(Hs.82396)
STRUCTURES  PDB: 1VPT  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.7.19
            WIT (What Is There) Metabolic Reconstruction: 2.7.7.19
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