ENTRY       EC 2.7.3.2
NAME        Creatine kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with a nitrogenous group as acceptor
SYSNAME     ATP:creatine N-phosphotransferase
REACTION    ATP + Creatine = ADP + Phosphocreatine
SUBSTRATE   ATP
            Creatine
            N-Ethylglycocyamine
PRODUCT     ADP
            Phosphocreatine
COMMENT     N-Ethylglycocyamine can also act as acceptor.
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
            PATH: MAP00330  Arginine and proline metabolism
DISEASE     MIM: 123280  Creatine kinase, brain type
            MIM: 123290  Creatine kinase, mitochondrial
            MIM: 123295  Creatine kinase, mitochondrial-2 (sarcomeric)
            MIM: 123310  Creatine kinase, muscle type
MOTIF       PS: PS00112  C-P-x(0,1)-[ST]-N-[IL]-G-T
GENES       HSA: CKB(CKBB) CKBE CKM(CKMM) CKMT1(CKMT) CKMT2(SMTCK)
STRUCTURES  PDB: 1CRK  
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.3.2
            WIT (What Is There) Metabolic Reconstruction: 2.7.3.2
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