ENTRY       EC 2.7.2.11
NAME        Glutamate 5-kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with a carboxyl group as acceptor
SYSNAME     ATP:L-glutamate 5-phosphotransferase
REACTION    ATP + L-Glutamate = ADP + L-Glutamate 5-phosphate
SUBSTRATE   ATP
            L-Glutamate
PRODUCT     ADP
            L-Glutamate 5-phosphate
COMMENT     Product rapidly cyclizes to 5-oxoproline and orthophosphate
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
DISEASE     MIM: 138250  Pyrroline-5-carboxlate synthetase; ?P5CS deficiency
                         (1)
MOTIF       PS: PS00902  [GST]-x(2)-G-x-G-G-M-x-[STA]-K-[LIVM]-x-A-[TA]-x(2)-A-
                         x(3)-G
GENES       ECO: b0242(proB)
            HIN: HI0900(proB)
            BSU: proB
            SYN: slr2035(proB)
            SCE: YDR300C(PRO1)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.2.11
            WIT (What Is There) Metabolic Reconstruction: 2.7.2.11
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