ENTRY       EC 2.7.1.95
NAME        Kanamycin kinase
            Neomycin-kanamycin phosphotransferase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with an alcohol group as acceptor
SYSNAME     ATP:kanamycin O3'-phosphotransferase
REACTION    ATP + Kanamycin = ADP + Kanamycin 3'-phosphate
SUBSTRATE   ATP
            Kanamycin
            Neomycin
            Paromomycin
            Neamine
            Paromamine
            Vistamycin
            Gentamicin A
            Bitirosin
PRODUCT     ADP
            Kanamycin 3'-phosphate
COMMENT     Also acts on the antibiotics neomycin, paromomycin, neamine,
            paromamine, vistamycin and gentamicin A. An enzyme from
            Pseudomonas aeruginosa also acts on bitirosin.
MOTIF       PS: PS00109  [LIVMFYC]-x-[HY]-x-D-[LIVMFY]-[RSTAC]-x(2)-N-
                         [LIVMFYC](3)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.1.95
            WIT (What Is There) Metabolic Reconstruction: 2.7.1.95
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