ENTRY EC 2.7.1.30
NAME Glycerol kinase
CLASS Transferases
Transferring phosphorus-containing groups
Phosphotransferases with an alcohol group as acceptor
SYSNAME ATP:glycerol 3-phosphotransferase
REACTION ATP + Glycerol = ADP + sn-Glycerol 3-phosphate
SUBSTRATE ATP
UTP
Glycerol
L-Glyceraldehyde
Glycerone
PRODUCT ADP
sn-Glycerol 3-phosphate
COMMENT Glycerone and L-glyceraldehyde can act as acceptors; UTP (and,
in the case of the yeast enzyme, ITP and GTP) can act as donors.
PATHWAY PATH: MAP00561 Glycerolipid metabolism
DISEASE MIM: 307030 Glycerol kinase deficiency; Glycerol kinase deficiency
(3)
MOTIF PS: PS00445 [GSA]-x-[LIVMFYW]-x-G-[LIVM]-x(7,8)-[HDENQ]-[LIVMF]-
x(2)-[AS]-[TAIVM]-[LIVMFY]-[DEQ]
PS: PS00933 [MFYGS]-x-[PST]-x(2)-K-[LIVMFYW]-x-W-[LIVMF]-x-
[DENQTR]-[ENQH]
GENES ECO: b3926(glpK)
HIN: HI0691(glpK)
BSU: glpK
MGE: MG038(glpK)
MPN: D09_orf508(glpK)
SYN: slr1672(glpK)
SCE: YHL032C(GUT1)
HSA: GK(Hs.1466)
STRUCTURES PDB: 1GLA 1GLC 1GLD 1GLE 1GLB
DBLINKS University of Geneva ENZYME DATA BANK: 2.7.1.30
WIT (What Is There) Metabolic Reconstruction: 2.7.1.30
SCOP (Structural Classificaion of Proteins): 2.7.1.30
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