ENTRY       EC 2.7.1.141
NAME        [RNA-polymerase]-subunit kinase
            CTD kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with an alcohol group as acceptor
SYSNAME     ATP:[DNA-directed RNA polymerase] phosphotransferase
REACTION    ATP + [DNA-directed RNA polymerase] = ADP +
            Phospho-[DNA-directed RNA polymerase]
SUBSTRATE   ATP
            [DNA-directed RNA polymerase]
PRODUCT     ADP
            Phospho-[DNA-directed RNA polymerase]
COMMENT     The enzyme appears to be distinct from other protein
            phosphokinases.  It brings about multiple phosphorylation of the
            unique C-terminal repeat domain of the largest subunit of
            eukaryotic EC 2.7.7.6.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.1.141
            WIT (What Is There) Metabolic Reconstruction: 2.7.1.141
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