ENTRY       EC 2.7.1.135
NAME        Tau-protein kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with an alcohol group as acceptor
SYSNAME     ATP:tau-protein O-phosphotransferase
REACTION    ATP + tau-Protein = ADP + O-Phospho-tau-protein
SUBSTRATE   ATP
            tau-Protein
PRODUCT     ADP
            O-Phospho-tau-protein
EFFECTOR    Tublin
COMMENT     Activated by tublin.  DIfferent from EC 2.7.1.123: not activated
            by calmodulin, cyclic nucleotides or Ca2+.  Involved in the
            formation of paired helical filaments in brain.  See comment on
            EC 2.7.1.37.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.1.135
            WIT (What Is There) Metabolic Reconstruction: 2.7.1.135
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