ENTRY       EC 2.7.1.130
NAME        Tetraacyldisaccharide 4'-kinase
            Lipid-A 4'-kinase
CLASS       Transferases
            Transferring phosphorus-containing groups
            Phosphotransferases with an alcohol group as acceptor
SYSNAME     ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-
            $beta-D-1,6-glucosaminyl-beta-phosphate 4-O'-phosphotransferase
REACTION    ATP +
            2,3-Bis-(3-hydroxytetradecanoyl)-D-glucosaminyl-(beta-D-1,6)-2,3-
            $bis(3-hydroxy-tetradecanoyl)-D-glucosaminyl beta-phosphate =
            ADP +
            2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-
            $beta-D-glucosamine 1,4'-bisphosphate
SUBSTRATE   ATP
            2,3-Bis-(3-hydroxytetradecanoyl)-D-glucosaminyl-(beta-D-1,6)-2,3-
            $bis(3-hydroxy-tetradecanoyl)-D-glucosaminyl beta-phosphate
PRODUCT     ADP
            2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-
            $beta-D-glucosamine 1,4'-bisphosphate
COMMENT     Involved with EC 2.3.1.129 and 2.4.1.182 in the biosynthesis of
            the phosphorylated glycolipid, Lipid A, in the outer membrane of
            Escherichia coli.
PATHWAY     PATH: MAP00530  Aminosugars metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 2.7.1.130
            WIT (What Is There) Metabolic Reconstruction: 2.7.1.130
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