ENTRY       EC 2.6.1.57
NAME        Aromatic-amino-acid transaminase
CLASS       Transferases
            Transferring nitrogenous groups
            Transaminases
SYSNAME     Aromatic-amino-acid:2-oxoglutarate aminotransferase
REACTION    an Aromatic amino acid + 2-Oxoglutarate = an Aromatic oxo acid +
            L-Glutamate
SUBSTRATE   Aromatic amino acid
            2-Oxoglutarate
            Oxaloacetate
PRODUCT     Aromatic oxo acid
            L-Glutamate
            L-Aspartate
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. L-Methionine can also act as donor,
            more slowly; oxaloacetate can act as acceptor. Controlled
            proteolysis converts the enzyme into EC 2.6.1.1.
PATHWAY     PATH: MAP00400  Phenylalanine, tyrosine and tryptophan biosynthesis
MOTIF       PS: PS00105  [GS]-[LIVMFYTAC]-[GSTA]-K-x(2)-[GSALVN]-[LIVMFA]-x-
                         [GNAR]-x-R-[LIVMA]-[GA]
GENES       ECO: b4054(tyrB)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.6.1.57
            WIT (What Is There) Metabolic Reconstruction: 2.6.1.57
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