ENTRY       EC 2.6.1.51
NAME        Serine--pyruvate transaminase
CLASS       Transferases
            Transferring nitrogenous groups
            Transaminases
SYSNAME     L-Serine:pyruvate aminotransferase
REACTION    L-Serine + Pyruvate = 3-Hydroxypyruvate + L-Alanine
SUBSTRATE   L-Serine
            Pyruvate
PRODUCT     3-Hydroxypyruvate
            L-Alanine
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. The liver enzyme may be
            identical with EC 2.6.1.44.
PATHWAY     PATH: MAP00260  Glycine, serine and threonine metabolism
DISEASE     MIM: 259900  Alanine-glyoxylate aminotransferase, liver-specific
                         peroxisomal; Hyperoxaluria, primary, type 1 (3)
MOTIF       PS: PS00342  [SAGCN]-[RKH]-[LIVMAF]>
            PS: PS00595  [LIVMFYA](2)-x(2)-[GSTAC](2)-[HQR]-K-x(4,6)-G-x-[GSAT]-
                         x-[LIVMFYS]
DBLINKS     University of Geneva ENZYME DATA BANK: 2.6.1.51
            WIT (What Is There) Metabolic Reconstruction: 2.6.1.51
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