ENTRY       EC 2.6.1.44
NAME        Alanine--glyoxylate transaminase
CLASS       Transferases
            Transferring nitrogenous groups
            Transaminases
SYSNAME     L-Alanine:glyoxylate aminotransferase
REACTION    L-Alanine + Glyoxylate = Pyruvate + Glycine
SUBSTRATE   L-Alanine
            Glyoxylate
            2-Oxobutanoate
            3-Hydroxypyruvate
PRODUCT     Pyruvate
            Glycine
            L-Serine
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. With one component of the
            animal enzyme, 2-oxobutanoate can replace glyoxylate.
            A second component also catalyses the reaction of EC 2.6.1.51.
PATHWAY     PATH: MAP00252  Alanine and Aspartate metabolism
            PATH: MAP00260  Glycine, serine and threonine metabolism
MOTIF       PS: PS00342  [SAGCN]-[RKH]-[LIVMAF]>
            PS: PS00595  [LIVMFYA](2)-x(2)-[GSTAC](2)-[HQR]-K-x(4,6)-G-x-[GSAT]-
                         x-[LIVMFYS]
GENES       HSA: AGXT(SPAT)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.6.1.44
            WIT (What Is There) Metabolic Reconstruction: 2.6.1.44
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