ENTRY EC 2.6.1.36
NAME L-Lysine 6-transaminase
CLASS Transferases
Transferring nitrogenous groups
Transaminases
SYSNAME L-Lysine:2-oxoglutarate 6-aminotransferase
REACTION L-Lysine + 2-Oxoglutarate = L-2-Aminoadipate 6-semialdehyde +
L-Glutamate
SUBSTRATE L-Lysine
2-Oxoglutarate
PRODUCT L-2-Aminoadipate 6-semialdehyde
L-Glutamate
1-Piperideine 6-carboxylate
COFACTOR Pyridoxal phosphate
COMMENT A pyridoxal-phosphate protein. The product (allysine) is converted
into the intramolecularly dehydrated form, 1-piperideine
6-carboxylate.
PATHWAY PATH: MAP00300 Lysine biosynthesis
PATH: MAP00310 Lysine degradation
DBLINKS University of Geneva ENZYME DATA BANK: 2.6.1.36
WIT (What Is There) Metabolic Reconstruction: 2.6.1.36
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