ENTRY       EC 2.6.1.24
NAME        Diiodotyrosine transaminase
CLASS       Transferases
            Transferring nitrogenous groups
            Transaminases
SYSNAME     3,5-Diiodo-L-tyrosine:2-oxoglutarate aminotransferase
REACTION    3,5-Diiodo-L-tyrosine + 2-Oxoglutarate =
            3,5-Diiodo-4-hydroxyphenylpyruvate + L-Glutamate
SUBSTRATE   3,5-Diiodo-L-tyrosine
            2-Oxoglutarate
            3,5-Dichloro-L-tyrosine
            3,5-Dibromo-L-tyrosine
            3-Iodo-L-tyrosine
            Thyroxine
            Triiodothyronine
PRODUCT     3,5-Diiodo-4-hydroxyphenylpyruvate
            L-Glutamate
            3,5-Dichloro-4-hydroxyphenylpyruvate
            3,5-Dibromo-4-hydroxyphenylpyruvate
            3-Iodo-4-hydroxyphenylpyruvate
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. Also acts on 3,5-dichloro-,
            3,5-dibromo- and 3-iodo-L-tyrosine, thyroxine and
            triiodothyronine.
DBLINKS     University of Geneva ENZYME DATA BANK: 2.6.1.24
            WIT (What Is There) Metabolic Reconstruction: 2.6.1.24
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