ENTRY       EC 2.6.1.13
NAME        Ornithine--oxo-acid transaminase
CLASS       Transferases
            Transferring nitrogenous groups
            Transaminases
SYSNAME     L-Ornithine:2-oxo-acid aminotransferase
REACTION    L-Ornithine + a 2-Oxo acid = L-Glutamate 5-semialdehyde +
            an L-Amino acid
SUBSTRATE   L-Ornithine
            2-Oxo acid
PRODUCT     L-Glutamate 5-semialdehyde
            L-Amino acid
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. PQQ ?
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
            PATH: MAP00330  Arginine and proline metabolism
DISEASE     MIM: 258870  Ornithine aminotransferase; Gyrate atrophy of choroid
                         and retina with ornithinemia, B6 responsive or
                         unresponsive (3)
MOTIF       PS: PS00600  [LIVMFYW](2)-x-D-E-[LIVMA]-x(2)-[GP]-[LIVMFYWAG]-
                         x(0,1)-[SACR]-x-[GSAD]-x(12,16)-D-[LIVMFYW]-x(2,3)-
                         [GSA]-K-x(3)-[GSTADN]-[GSA]
GENES       ECO: b3073(ygjG) b3074(ygjH)
            BSU: rocD
            SCE: YLR438W(CAR2)
            HSA: OAT(Hs.75485)
DBLINKS     University of Geneva ENZYME DATA BANK: 2.6.1.13
            WIT (What Is There) Metabolic Reconstruction: 2.6.1.13
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