ENTRY       EC 2.5.1.29
NAME        Farnesyltranstransferase
            Geranylgeranyl-diphosphate synthase
CLASS       Transferases
            Transferring alkyl or aryl groups, other than methyl groups
SYSNAME     trans,trans-Farnesyl-diphosphate:isopentenyl-diphosphate
            $ farnesyltranstransferase
REACTION    trans,trans-Farnesyl diphosphate + Isopentenyl diphosphate =
            Pyrophosphate + Geranylgeranyl diphosphate
SUBSTRATE   trans,trans-Farnesyl diphosphate
            Isopentenyl diphosphate
PRODUCT     Pyrophosphate
            Geranylgeranyl diphosphate
COMMENT     Some forms of this enzyme will also use geranyl diphosphate and
            dimethylallyl diphosphate as donors; it will not use larger
            prenyl diphosphate as efficient donors.
PATHWAY     PATH: MAP00100  Sterol biosynthesis
            PATH: MAP00900  Terpenoid biosynthesis
MOTIF       PS: PS00444  [LIVMFY]-G-x(2)-[FY]-Q-[LIVM]-x-D-D-[LIVMFY]-x-[DNG]
            PS: PS00723  [LIVM](2)-x-D-D-x(2,4)-D-x(4)-R-R-G
DBLINKS     University of Geneva ENZYME DATA BANK: 2.5.1.29
            WIT (What Is There) Metabolic Reconstruction: 2.5.1.29
///