ENTRY EC 2.4.2.18
NAME Anthranilate phosphoribosyltransferase
Phosphoribosyl-anthranilate pyrophosphorylase
CLASS Transferases
Glycosyltransferases
Pentosyltransferases
SYSNAME N-(5-Phospho-D-ribosyl)-anthranilate:pyrophosphate phospho-
ribosyltransferase
REACTION N-(5-Phospho-D-ribosyl)anthranilate + Pyrophosphate = Anthranilate
+ 5-Phospho-alpha-D-ribose 1-diphosphate
SUBSTRATE N-(5-Phospho-D-ribosyl)anthranilate
Pyrophosphate
PRODUCT Anthranilate
5-Phospho-alpha-D-ribose 1-diphosphate
COMMENT In some organisms, this enzyme is part of a multifunctional
protein together with one or more other components of the system
for biosynthesis of tryptophan (EC 4.1.1.48, 4.1.3.27, 4.2.1.20,
5.3.1.24).
PATHWAY PATH: MAP00400 Phenylalanine, tyrosine and tryptophan biosynthesis
MOTIF PS: PS00442 [PAS]-[LIVMFYT]-[LIVMFY]-G-[LIVMFY]-C-[LIVMFYN]-G-x-
[QE]-x-[LIVMFA]
GENES MJA: MJ0234(trpD)
MTH: MTH1661(trpD)
ECO: b1263(trpD)
HIN: HI1389(trpD)
HPY: HP1281(trpD)
BSU: trpD
SYN: slr1867(trpD)
SCE: YDR354W(TRP4)
DBLINKS University of Geneva ENZYME DATA BANK: 2.4.2.18
WIT (What Is There) Metabolic Reconstruction: 2.4.2.18
///
DBGET integrated database retrieval system,
GenomeNet