ENTRY EC 2.1.3.7
NAME 3-Hydroxymethylcephem carbamoyltransferase
CLASS Transferases
Transferring one-carbon groups
Carboxyl- and carbamoyltransferases
SYSNAME Carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate
$ carbamoyltransferase
REACTION Carbamoyl phosphate + a 3-Hydroxymethyl ceph-3-em-4-carboxylate =
Orthophosphate + a 3-Carbamoyloxymethylcephem
SUBSTRATE Carbamoyl phosphate
3-Hydroxymethyl ceph-3-em-4-carboxylate
PRODUCT Orthophosphate
3-Carbamoyloxymethylcephem
EFFECTOR ATP
COMMENT Acts on a wide range of 3-hydroxymethylcephems (a subclass of the
cephalosporin antibiotics). Activated by ATP.
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.3.7
WIT (What Is There) Metabolic Reconstruction: 2.1.3.7
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