ENTRY       EC 2.1.2.5
NAME        Glutamate formiminotransferase
            Glutamate formyltransferase
CLASS       Transferases
            Transferring one-carbon groups
            Hydroxymethyl-, formyl- and related transferases
SYSNAME     5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase
REACTION    5-Formiminotetrahydrofolate + L-Glutamate = Tetrahydrofolate +
            N-Formimino-L-glutamate
SUBSTRATE   5-Formiminotetrahydrofolate
            L-Glutamate
            5-Formyltetrahydrofolate
PRODUCT     Tetrahydrofolate
            N-Formimino-L-glutamate
            N-Formyl-L-glutamate
COFACTOR    Pyridoxal phosphate
COMMENT     A pyridoxal-phosphate protein. Also catalyses formyl transfer
            from 5-formyltetrahydrofolate to L-glutamate (a reaction formerly
            listed as EC 2.1.2.6). In eukaryotes occurs as a bifunctional
            enzyme also having formiminotetrahydrofolate cyclodeaminase
            activity (EC 4.3.1.4).
PATHWAY     PATH: MAP00340  Histidine metabolism
            PATH: MAP00670  One carbon pool by folate
DBLINKS     University of Geneva ENZYME DATA BANK: 2.1.2.5
            WIT (What Is There) Metabolic Reconstruction: 2.1.2.5
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