ENTRY EC 2.1.1.90
NAME Methanol--5-hydroxybenzimidazolylcobamide Co-methyltransferase
CLASS Transferases
Transferring one-carbon groups
Methyltransferases
SYSNAME Methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase
REACTION Methanol + 5-Hydroxybenzimidazolylcobamide =
Co-Methyl-Co-5-hydroxybenzimidazolylcob(I)amide + H2O
SUBSTRATE Methanol
5-Hydroxybenzimidazolylcobamide
PRODUCT Co-Methyl-Co-5-hydroxybenzimidazolylcob(I)amide
H2O
COMMENT The enzyme form Methanosarcina barkeri contains 3-4 molecules of
bound 5-hydroxybenzimidazolylcobamide which act as methyl
acceptor. Inactivated by oxygen and other oxidizing agents, and
reactivated by catalytic amounts of ATP and hydrogen.
DBLINKS University of Geneva ENZYME DATA BANK: 2.1.1.90
WIT (What Is There) Metabolic Reconstruction: 2.1.1.90
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