ENTRY       EC 1.8.4.5
NAME        Methionine-S-oxide reductase
            Methyl sulfoxide reductase I and II
CLASS       Oxidoreductases
            Acting on a sulfur group of donors
            With a disulfide as acceptor
SYSNAME     L-Methionine:oxidized-thioredoxin S-oxidoreductase
REACTION    L-Methionine + Oxidized thioredoxin = L-Methionine S-oxide +
            Reduced thioredoxin
SUBSTRATE   L-Methionine
            Oxidized thioredoxin
PRODUCT     L-Methionine S-oxide
            Reduced thioredoxin
            Dithiothreitol
COMMENT     In the reverse reaction dithiothreitol can replace reduced
            thioredoxin, and other methyl sulfoxides can replace methionine
            sulfoxide.
PATHWAY     PATH: MAP00271  Methionine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.8.4.5
            WIT (What Is There) Metabolic Reconstruction: 1.8.4.5
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