ENTRY       EC 1.6.6.4
NAME        Nitrite reductase (NAD(P)H)
CLASS       Oxidoreductases
            Acting on NADH or NADPH
            With a nitrogenous group as acceptor
SYSNAME     NAD(P)H:nitrite oxidoreductase
REACTION    3 NADH + Nitrite = 3 NAD+ + NH4OH + H2O;
            3 NADPH + Nitrite = 3 NADP+ + NH4OH + H2O
SUBSTRATE   NADPH
            NADH
            Nitrite
PRODUCT     NADP+
            NAD+
            NH4OH
            H2O
COFACTOR    FAD
            Siroheme
            Iron
COMMENT     A flavoprotein containing a siroheme and non-heme iron.
PATHWAY     PATH: MAP00910  Nitrogen metabolism
MOTIF       PS: PS00365  [STV]-G-C-x(3)-C-x(6)-[DE]-[LIVMF]-[GAT]-[LIVMF]
GENES       ECO: b3365(nirB) b3366(nirD) b3367(nirC)
            BSU: nasB(nasBA) nasD(nasBC) nasE(nasBD)
DBLINKS     University of Geneva ENZYME DATA BANK: 1.6.6.4
            WIT (What Is There) Metabolic Reconstruction: 1.6.6.4
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