ENTRY EC 1.5.99.7
NAME Trimethylamine dehydrogenase
CLASS Oxidoreductases
Acting on the CH-NH group of donors
With other acceptors
SYSNAME Trimethylamine:(acceptor) oxidoreductase (demethylating)
REACTION Trimethylamine + H2O + Acceptor = Dimethylamine + Formaldehyde
+ Reduced acceptor
SUBSTRATE Trimethylamine
Trimethylamine(alkyl-substituted derivatives)
H2O
Acceptor
Phenazine methosulfate
2,6-Dichloroindophenol
PRODUCT Dimethylamine
Formaldehyde
Reduced acceptor
COMMENT A number of alkyl-substituted derivatives of trimethylamine can
also act as electron donor, phenazine methosulfate and
2,6-dichloroindophenol can act as electron acceptors.
PATHWAY PATH: MAP00680 Methane metabolism
STRUCTURES PDB: 2TMD
DBLINKS University of Geneva ENZYME DATA BANK: 1.5.99.7
WIT (What Is There) Metabolic Reconstruction: 1.5.99.7
SCOP (Structural Classificaion of Proteins): 1.5.99.7
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