ENTRY       EC 1.5.99.6
NAME        Spermidine dehydrogenase
CLASS       Oxidoreductases
            Acting on the CH-NH group of donors
            With other acceptors
SYSNAME     Spermidine:(acceptor) oxidoreductase
REACTION    Spermidine + Acceptor + H2O = 1,3-Diaminopropane +
            4-Aminobutanal + Reduced acceptor
SUBSTRATE   Spermidine
            Acceptor
            H2O
            Ferricyanide
            2,6-Dichloroindophenol
            Cytochrome c
PRODUCT     1,3-Diaminopropane
            4-Aminobutanal
            Reduced acceptor
COFACTOR    FAD
            Heme
COMMENT     A flavohemoprotein (FAD). Ferricyanide, 2,6-dichloroindophenol
            and cytochrome c can act as acceptor. 4-Aminobutanal condenses
            non-enzymically to 1-pyrroline.
PATHWAY     PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00410  beta-Alanine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.5.99.6
            WIT (What Is There) Metabolic Reconstruction: 1.5.99.6
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