ENTRY EC 1.5.1.22
NAME Strombine dehydrogenase
CLASS Oxidoreductases
Acting on the CH-NH group of donors
With NAD+ or NADP+ as acceptor
SYSNAME N-(Carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)
REACTION N-(Carboxymethyl)-D-alanine + NAD+ + H2O = Glycine + Pyruvate +
NADH
SUBSTRATE N-(Carboxymethyl)-D-alanine
NAD+
H2O
2,2'-Iminodipropanoate
PRODUCT Glycine
Pyruvate
NADH
L-Alanine
COMMENT Also catalyses the reaction of EC 1.5.1.17, more slowly. Does
not act on L-strombine.
DBLINKS University of Geneva ENZYME DATA BANK: 1.5.1.22
WIT (What Is There) Metabolic Reconstruction: 1.5.1.22
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