ENTRY       EC 1.4.3.4
NAME        Amine oxidase (flavin-containing)
            Monoamine oxidase
            Tyramine oxidase
            Tyraminase
            Amine oxidase
            Adrenalin oxidase
CLASS       Oxidoreductases
            Acting on the CH-NH2 group of donors
            With oxygen as acceptor
SYSNAME     Amine:oxygen oxidoreductase(deaminating)(flavin-containing)
REACTION    RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2
SUBSTRATE   RCH2NH2
            H2O
            O2
            Primary amine
            Secondary amine
            Tertiary amine
PRODUCT     RCHO
            NH3
            H2O2
COFACTOR    FAD
COMMENT     A flavoprotein(FAD). Acts on primary amines, and usually also
            on some secondary and tertiary amines.
PATHWAY     PATH: MAP00260  Glycine, serine and threonine metabolism
            PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00340  Histidine metabolism
            PATH: MAP00350  Tyrosine metabolism
            PATH: MAP00360  Phenylalanine metabolism
            PATH: MAP00380  Tryptophan metabolism
DISEASE     MIM: 309850  Monoamine oxidase A; Brunner syndrome (3)
            MIM: 309860  Monoamine oxidase B
MOTIF       PS: PS00342  [SAGCN]-[RKH]-[LIVMAF]>
GENES       HSA: MAOA(Hs.1782) MAOB(Hs.82163)
DBLINKS     University of Geneva ENZYME DATA BANK: 1.4.3.4
            WIT (What Is There) Metabolic Reconstruction: 1.4.3.4
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