ENTRY       EC 1.4.3.3
NAME        D-Amino-acid oxidase
CLASS       Oxidoreductases
            Acting on the CH-NH2 group of donors
            With oxygen as acceptor
SYSNAME     D-Amino-acid:oxygen oxidoreductase (deaminating)
REACTION    D-Amino acid + H2O + O2 = 2-Oxo acid + NH3 + H2O2
SUBSTRATE   D-Amino acid
            Glycine
            H2O
            O2
PRODUCT     2-Oxo acid
            NH3
            H2O2
COFACTOR    FAD
COMMENT     A flavoprotein (FAD).
            Wide specificity for D-amino acids. Also acts on glycine.
PATHWAY     PATH: MAP00260  Glycine, serine and threonine metabolism
            PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00472  D-Arginine and D-ornithine metabolism
DISEASE     MIM: 124050  D-amino-acid oxidase
MOTIF       PS: PS00342  [SAGCN]-[RKH]-[LIVMAF]>
            PS: PS00677  [LIVM](2)-H-[NH]-Y-G-x-[GSA](2)-x-G-x(5)-G-x-A
GENES       HSA: DAO(DAMOX)
STRUCTURES  PDB: 1AA8  1KIF  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.4.3.3
            WIT (What Is There) Metabolic Reconstruction: 1.4.3.3
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