ENTRY       EC 1.4.1.3
NAME        Glutamate dehydrogenase (NAD(P)+)
            Glutamic dehydrogenase
CLASS       Oxidoreductases
            Acting on the CH-NH2 group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     L-Glutamate:NAD(P)+ oxidoreductase (deaminating)
REACTION    L-Glutamate + H2O + NAD+ or NADP+ = 2-Oxoglutarate + NH3 +
            NADH or NADPH
SUBSTRATE   L-Glutamate
            H2O
            NAD+
            NADP+
PRODUCT     2-Oxoglutarate
            NH3
            NADH
            NADPH
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
            PATH: MAP00251  Glutamate metabolism
            PATH: MAP00330  Arginine and proline metabolism
            PATH: MAP00471  D-Glutamine and D-glutamate metabolism
            PATH: MAP00910  Nitrogen metabolism
DISEASE     MIM: 138130  Glutamate dehydrogenase-1
MOTIF       PS: PS00074  [LIV]-x(2)-G-G-[SAG]-K-x-[GV]-x(3)-[DNS]-[PL]
GENES       HSA: GLUD1(GLUD)
STRUCTURES  PDB: 1GTM  
DBLINKS     University of Geneva ENZYME DATA BANK: 1.4.1.3
            WIT (What Is There) Metabolic Reconstruction: 1.4.1.3
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