ENTRY EC 1.2.99.3
NAME Aldehyde dehydrogenase (pyrroloquinoline-quinone)
Aldehyde dehydrogenase (acceptor)
CLASS Oxidoreductases
Acting on the aldehyde or oxo group of donors
With other acceptors
SYSNAME Aldehyde:(pyrroloquinoline-quinone) oxidoreductase
REACTION Aldehyde + Acceptor + H2O = Carboxylate + Reduced acceptor
SUBSTRATE Aldehyde
Acceptor
Aromatic aldehyde
H2O
Glyoxylate
Glyceraldehyde
Phenazine methosulfate
PRODUCT Carboxylate
Reduced acceptor
COFACTOR PQQ
COMMENT A quinoprotein. Wide specificity; acts on straight-chain
aldehydes up to C10, aromatic aldehydes, glyoxylate and
glyceraldehyde.
PATHWAY PATH: MAP00071 Fatty acid metabolism
PATH: MAP00620 Pyruvate metabolism
PATH: MAP00640 Propanoate metabolism
PATH: MAP00650 Butanoate metabolism
DBLINKS University of Geneva ENZYME DATA BANK: 1.2.99.3
WIT (What Is There) Metabolic Reconstruction: 1.2.99.3
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