ENTRY       EC 1.2.99.2
NAME        Carbon monoxide dehydrogenase
CLASS       Oxidoreductases
            Acting on the aldehyde or oxo group of donors
            With other acceptors
SYSNAME     Carbon-monoxide:(acceptor) oxidoreductase
REACTION    CO + H2O + Acceptor = CO2 + Reduced acceptor
SUBSTRATE   CO
            H2O
            Acceptor
            Methyl viologen
PRODUCT     CO2
            Reduced acceptor
COFACTOR    Nickel
            Zinc
            Iron
COMMENT     Contains nickel, zinc and non-heme iron. Methyl viologen can act
            as acceptor. The enzyme from Clostridium sp. also catalyses an
            exchange reaction of carbon between C-1 of acetyl-CoA and CO;
            involved in the synthesis of acetyl-CoA from CO2 and H2.
PATHWAY     PATH: MAP00680  Methane metabolism
MOTIF       PS: PS00198  C-x(2)-C-x(2)-C-x(3)-C-[PEG]
GENES       MJA: MJ0152 MJ0153(cdhA) MJ0154 MJ0156 MJ0728
            MTH: MTH1708 MTH1709 MTH1710
DBLINKS     University of Geneva ENZYME DATA BANK: 1.2.99.2
            WIT (What Is There) Metabolic Reconstruction: 1.2.99.2
///