ENTRY       EC 1.2.2.2
NAME        Pyruvate dehydrogenase (cytochrome)
            Pyruvate dehydrogenase
            Pyruvic dehydrogenase
CLASS       Oxidoreductases
            Acting on the aldehyde or oxo group of donors
            With a cytochrome as acceptor
SYSNAME     Pyruvate:ferricytochrome-b1 oxidoreductase
REACTION    Pyruvate + Ferricytochrome b1 + H2O = Acetate + CO2 +
            Ferrocytochrome b1
SUBSTRATE   Pyruvate
            Ferricytochrome b1
            H2O
PRODUCT     Acetate
            CO2
            Ferrocytochrome b1
COFACTOR    Thiamine diphosphate
            FAD
COMMENT     A flavoprotein requiring thiamine diphosphate.
PATHWAY     PATH: MAP00620  Pyruvate metabolism
MOTIF       PS: PS00187  [LIVMF]-[GSA]-x(5)-P-x(4)-[LIVMFYW]-x-[LIVMF]-x-G-D-
                         [GSA]-[GSAC]
GENES       ECO: b0871(poxB)
            BSU: ydaP
DBLINKS     University of Geneva ENZYME DATA BANK: 1.2.2.2
            WIT (What Is There) Metabolic Reconstruction: 1.2.2.2
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