ENTRY       EC 1.2.1.49
NAME        2-Oxoaldehyde dehydrogenase (NADP+)
            alpha-Ketoaldehyde dehydrogenase
            Methylglyoxal dehydrogenase
CLASS       Oxidoreductases
            Acting on the aldehyde or oxo group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     2-Oxoaldehyde:NADP+ oxidoreductase
REACTION    a 2-Oxoaldehyde + NADP+ + H2O = a 2-Oxo acid + NADPH
SUBSTRATE   2-Oxoaldehyde
            NADP+
            H2O
PRODUCT     2-Oxo acid
            NADPH
COMMENT     Not identical with EC 1.2.1.23.
PATHWAY     PATH: MAP00620  Pyruvate metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.2.1.49
            WIT (What Is There) Metabolic Reconstruction: 1.2.1.49
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