ENTRY       EC 1.2.1.46
NAME        Formaldehyde dehydrogenase
CLASS       Oxidoreductases
            Acting on the aldehyde or oxo group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     Formaldehyde:NAD+ oxidoreductase
REACTION    Formaldehyde + NAD+ + H2O = Formate + NADH
SUBSTRATE   Formaldehyde
            NAD+
            H2O
PRODUCT     Formate
            NADH
COMMENT     Unlike EC 1.2.1.1, this enzyme from Pseudomonas does not need
            reduced glutathione.
PATHWAY     PATH: MAP00220  Urea cycle and metabolism of amino groups
            PATH: MAP00680  Methane metabolism
MOTIF       PS: PS00059  G-H-E-x(2)-G-x(5)-[GA]-x(2)-[IVAC]
DBLINKS     University of Geneva ENZYME DATA BANK: 1.2.1.46
            WIT (What Is There) Metabolic Reconstruction: 1.2.1.46
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