ENTRY       EC 1.17.99.1
NAME        4-Cresol dehydrogenase (hydroxylating)
            p-Cresol methylhydroxylase
CLASS       Oxidoreductases
            Acting on -CH2- groups
            With other acceptors
SYSNAME     4-Cresol:(acceptor) oxidoreductase (methyl-hydroxylating)
REACTION    4-Cresol + Acceptor + H2O = 4-Hydroxybenzaldehyde +
            Reduced acceptor
SUBSTRATE   4-Cresol
            4-Hydroxybenzaldehyde
            Acceptor
            Phenazine methosulfate
            H2O
PRODUCT     4-Hydroxybenzaldehyde
            Reduced acceptor
COFACTOR    FAD
            Cytochrome c
COMMENT     A flavocytochrome c (FAD). Phenazine methosulfate can act as
            acceptor. A quinone methide is probably formed as intermediate;
            the product is oxidized further to 4-hydroxybenzoate
DBLINKS     University of Geneva ENZYME DATA BANK: 1.17.99.1
            WIT (What Is There) Metabolic Reconstruction: 1.17.99.1
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