ENTRY       EC 1.14.99.7
NAME        Squalene monooxygenase
            Squalene epoxidase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            Miscellaneous
SYSNAME     Squalene,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)
REACTION    Squalene + AH2 + O2 = (S)-Squalene-2,3-epoxide + A + H2O
SUBSTRATE   Squalene
            AH2
            O2
PRODUCT     (S)-Squalene-2,3-epoxide
            A
            H2O
COFACTOR    FAD
COMMENT     A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7,
            was formerly known as squalene oxydocyclase.
PATHWAY     PATH: MAP00100  Sterol biosynthesis
            PATH: MAP00900  Terpenoid biosynthesis
GENES       SCE: YGR175C(ERG1)
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.99.7
            WIT (What Is There) Metabolic Reconstruction: 1.14.99.7
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