ENTRY EC 1.14.99.6
NAME Acyl-[acyl-carrier-protein] desaturase
Stearyl-ACP desaturase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
Miscellaneous
SYSNAME Acyl-[acyl-carrier-protein],hydrogen-donor:oxygen oxidoreductase
REACTION Stearoyl-[acyl-carrier protein] + AH2 + O2 =
Oleoyl-[acyl-carrier protein] + A + 2 H2O
SUBSTRATE Stearoyl-[acyl-carrier protein]
AH2
O2
Stearoyl-CoA
PRODUCT Oleoyl-[acyl-carrier protein]
A
H2O
Oleoyl-CoA
COFACTOR Ferredoxin
COMMENT The enzyme from safflower is specific for stearoyl-CoA; that
from Euglena acts on derivatives of a number of long-chain fatty
acids. Requires ferredoxin.
MOTIF PS: PS00574 [ST]-[SA]-x(3)-[QR]-[LI]-x(5,6)-D-Y-x(2)-[LIVMFYW]-
[LIVM]-[DE]
STRUCTURES PDB: 1AFR
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.99.6
WIT (What Is There) Metabolic Reconstruction: 1.14.99.6
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