ENTRY EC 1.14.99.19
NAME Plasmanylethanolamine desaturase
Alkylacylglycerophosphoethanolamine desaturase
CLASS Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
Miscellaneous
SYSNAME O-1-Alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,
$hydrogen-donor:oxygen oxidoreductase
REACTION O-1-Alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 =
O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
SUBSTRATE O-1-Alkyl-2-acyl-sn-glycero-3-phosphoethanolamine
AH2
O2
NADH
NADPH
PRODUCT O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine
A
H2O
NAD+
NADP+
COFACTOR Manganese
ATP
COMMENT Requires NADPH or NADH. May involve cytochrome b5. Requires Mg2+
and ATP.
DBLINKS University of Geneva ENZYME DATA BANK: 1.14.99.19
WIT (What Is There) Metabolic Reconstruction: 1.14.99.19
///
DBGET integrated database retrieval system,
GenomeNet