ENTRY       EC 1.14.99.12
NAME        4-Androstene-3,17-dione monooxygenase
            Androstene-3,17-dione hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            Miscellaneous
SYSNAME     Androst-4-ene-3,17-dione,hydrogen-donor:oxygen oxidoreductase
            (13-hydroxylating, lactonizing)
REACTION    Androst-4-ene-3,17-dione + AH2 + O2 =
            3-Oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
SUBSTRATE   Androst-4-ene-3,17-dione
            AH2
            O2
PRODUCT     3-Oxo-13,17-secoandrost-4-ene-17,13alpha-lactone
            A
            H2O
PATHWAY     PATH: MAP00150  Androgen and estrogen metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.99.12
            WIT (What Is There) Metabolic Reconstruction: 1.14.99.12
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