ENTRY       EC 1.14.16.6
NAME        Mandelate 4-monooxygenase
            L-Mandelate 4-hydroxylase
CLASS       Oxidoreductases
            Acting on paired donors with incorporation of molecular oxygen
            With reduced pteridine as one donor, and incorporation of
            one atom of oxygen
SYSNAME     (S)-2-Hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen
            $ oxidoreductase (4-hydroxylating)
REACTION    (S)-2-Hydroxy-2-phenylacetate + Tetrahydrobiopterin + O2 =
            (S)-4-Hydroxymandelate + Dihydrobiopterin + H2O
SUBSTRATE   (S)-2-Hydroxy-2-phenylacetate
            Tetrahydrobiopterin
            O2
PRODUCT     (S)-4-Hydroxymandelate
            Dihydrobiopterin
            H2O
COFACTOR    Iron
COMMENT     Requires Fe2+.
PATHWAY     PATH: MAP00360  Phenylalanine metabolism
DBLINKS     University of Geneva ENZYME DATA BANK: 1.14.16.6
            WIT (What Is There) Metabolic Reconstruction: 1.14.16.6
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